The EUCROF Association

Welcome to the website of EUCROF


EUCROF was founded in October 2005.


The aims and objectives of EUCROF were defined as follows:

  • Promote clinical research of high quality in Europe in general and in the European Union in particular;
  • Form a legal entity to represent the interests of CROs in the EU, for example, in transactions with regulatory bodies, the pharmaceutical-biotechnology industry and the medical research community;
  • Promote a close relationship and mutual understanding between the national member associations and the above-mentioned bodies;
  • Promote the exchange of information between member associations;
  • Develop training and educational programmes for clinical research, and assist the national member associations in setting up such programmes and ensuring their quality;
  • Distribute information on developments in clinical research to health professionals;
  • Organise international conferences and meetings.


Furthermore, the Federation's objectives include: discussions on selected topics with representatives of the pharmaceutical industry e.g. PCMG (Pharmaceutical Contract Management Group) to enhance business relations and identify common concerns, support more productive discussions with European bodies (EMEA/EU Commission), and endeavour to develop transcontinental relationships with other associations e.g. with ACRO (Association of Clinical Research Organisations) in the USA and JCROA (Japanese Clinical Research Organization) in Japan.

The Federation consists of Members from 12 EU countries: Belgium (BeCRO), Czech Republic (ACRO-CZ), France (AFCROs), Germany (BVMA), Greece (HACRO), Italy (AICRO), Romania (ACCSCR), Slovakia (SACROP), Spain (AECIC), The Netherlands (ACRON), Turkey (SAKDER) and UK (CCRA). The Federation has also 13 Associate Members in Albania, Austria, Bulgaria, Croatia, Denmark, Georgia, Serbia, Spain, Sweden, Switzerland, Ukraine and UK (2). It stands for 350 member-CROs and over 25,000 employees.

Since December 2006, the Federation is managed by an Executive Board (see here below) which holds monthly meetings. Each year, the Federation organizes two General Meetings (in Spring and Winter) with all its Members.


Definition of CRO: “A Contract Research Organisation (also called Clinical Research Organisation, CRO), is a person or an organisation (including commercial, academic and non-profit)  that provides services to industry and other stakeholders such as governmental organisations, foundations or hospitals, on a contract basis and within the scope of clinical research (experimental or observational) as well as other activities in connected domains.” 


EUCROF has 11 Working Groups:

  1. Clinical Trials Legislation: This group focuses on any proposed changes to Regulations and Guidelines for Clinical Trials - predominantly in the EU, but also elsewhere in the world. This group actively participates public in consultations and prepares comments for feedback to the European Medicines Agency (EMA) and other regulators.
  2. Communication: This group is focused on the effective and timely communication to EUCROF’s Members and stakeholders of all of the Federation’s initiatives, activities and important news to facilitate increased awareness and the achievement of its set objectives.
  3. Early Phase: This group evaluates and compares current practices within the bio-equivalence studies and the Phase I studies in Europe;
  4. Events & Training: This group establishes educational webinars throughout the year for its members and wider audience to provide training and increased awareness of key topics in clinical research.
  5. Innovative Medicine: This group is focused on Advanced Therapies Medicinal Products. The goal of this group is to identify, examine and provide solutions to the principal issues identified in ATMPs development and regulation, in constant dialogue and collaboration with the Industry and European Authorities.
  6. Late Phase: This group promotes good practices in the conduct of Late Phase studies in Europe - with particular reference to observational ones - through the sharing of knowledge, competence, expertise and skills, also speaking in congresses/conferences and participating EMA public consultations.
  7. Medical Device: This provides a forum for discussion of various aspects of clinical research associated with Medical Devices and IVD. Its further objective is to interact and share experiences with other stakeholders involved in this area.
  8. New Technologies: this group evaluates current and expected new technologies and evaluates how these can benefit and impact the clinical trial environment.
  9. Patients' Association: This group fosters actual and confident collaboration with patients in clinical research.
  10. Paediatric: this group works closely with authorities, paediatric networks, and associations such as EFGCP to improve paediatric research. The group collects and analyses information on paediatric research that it shares via trainings, publications, presentations at conferences. The group participates in initiatives set up to improve research in children and to develop better medicines for children.
  11. Pharmacovigilance: This group focuses on management of pharmacovigilance services throughout the product lifecycle which are increasingly undertaken by the CRO sector for the pharma & biotech industry, including current and future best practices as well as regulations for this critical area


EUCROF is a stakeholder of European Regulatory Authorities:

  • EUCROF has been integrally involved in stakeholder meetings with the EMA to discuss the implementation of the forthcoming EU Clinical Trials Regulation. Over the last 2 years EUCROF has been able to work with other stakeholder groups to influence and shape important aspects of the planned implementation, in particular the transparency requirements of the new Regulation. These meetings will continue until at least the planned implementation of the Regulation.
  • EUCROF was invited by the EMA to participate in the User Acceptance Testing (UAT) of the clinical trial portal and database and contribute to its on-going development. So far over 50 EUCROF testers have been involved in 46 UATs during 2016, 2017 with more follow in 2018.
  • EUCROF participated in the EMA Workshop on Guideline for first-in-man clinical trials for potential high-risk medicinal products in June 2007;
  • EUCROF was invited to participate in a European Commission - EMA Conference on the Operation of the Clinical Trials Directive (Directive 2001/20/EC) and Perspectives for the Future in October 2007;
  • EUCROF met Mr Fergus Sweeney (Inspections Sector) in July 2008. The objective of this meeting was to establish a permanent working relationship;
  • EUCROF is now a well-known and recognised European representative for CROs, giving them a voice in the EU.

Executive Board

  • President, Martine DEHLINGER-KREMER (Germany)
  • Vice-President, Stefano MARINI (Italy)
  • Secretary, Simon LEE (UK)
  • Treasurer, Yoani MATSAKIS (France)
  • Member, Christophe GOLENVAUX (Belgium)


EUCROF Secretariat

Assia Rosati - EUCROF

Mobile: +39 349 858 6648

Email: This email address is being protected from spambots. You need JavaScript enabled to view it. - website:



The Executive Board

Dr Martine Dehlinger-Kremer


German Federal Association of Contract Research Organisations (BVMA)

Stefano Marini


Associazione Italiana Contract Research Organization (AICRO)

Yoani Matsakis


Association Française des CROs (AFCROS)

Simon Lee


Clinical and Contract Research Association (CCRA)
United Kingdom

Christophe Golenvaux


The Belgian Association of CROs (BeCRO)

Mission Statement

The objective of EUCROF (the European CRO Federation), a non-profit organization founded in 2005, is to promote Clinical Research by improving the knowledge, competence/expertise and skills of Contract/Clinical Research Organisations (CROs) in Europe.

The Federation represents and supports the interests of CROs in Europe towards regulatory bodies, the pharmaceutical, biotech, medical device and other healthcare-related industry within the field of clinical research, as well as the medical and affiliated research community. EUCROF organises and supports training and education programs to increase the quality of clinical research and to improve collaboration and interaction amongst all stakeholders in the field of Clinical Research in Europe. Active participation in international congresses and meetings further underlines the significant role of CROs in Clinical Research in Europe.

Regulatory Authorities recognize EUCROF as the representative for European-based CROs, regularly calling upon EUCROF to contribute to the never-ending debate on the improvement of rules and regulations.